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SUVN-502 mesylate

CAS No. 1791396-46-7

SUVN-502 mesylate ( SUVN502 )

产品货号. M12698 CAS No. 1791396-46-7

SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2406 有现货
50MG ¥9558 有现货
100MG ¥14499 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SUVN-502 mesylate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
  • 产品描述
    SUVN-502 (SUVN502)is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
  • 同义词
    SUVN502
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT Receptor
  • 研究领域
    Neurological Disease
  • 适应症
    Alzheimer Disease

化学信息

  • CAS Number
    1791396-46-7
  • 分子量
    574.51
  • 分子式
    C22H28BrN3O6S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br.CS(=O)(=O)O.CS(=O)(=O)O
  • 化学全称
    1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole methanesulfonate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
产品手册
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